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Transamine 500mg Tablet Specification

  • Requires Prescription (YES/NO): Yes

  • Generics: Tranexamic Acid

  • Used For: Control of excessive bleeding (e.g. heavy periods, surgery, trauma, dental bleeding)

  • Class: Antifibrinolytic Agent


 How It Works

Tranexamic Acid works by inhibiting fibrinolysis—it blocks the breakdown of fibrin clots by stopping plasminogen from converting to plasmin. This action helps to stabilize blood clots and reduce excessive bleeding during or after surgery, trauma, or menstruation.

Usage and Safety

Dosage:

  • Heavy menstrual bleeding: 500–1000 mg 2–3 times a day for up to 4 days

  • Surgical bleeding or trauma: As prescribed by the physician

  • Should be taken with water, with or without food

Side Effects:

  • Common: Nausea, diarrhea, headache

  • Rare: Visual disturbances, dizziness

  • Very rare: Allergic reaction, thromboembolic events (e.g., blood clots)


 Indication

Transamine 500mg is indicated for:

  • Menorrhagia (heavy menstrual bleeding)

  • Surgical bleeding control

  • Postpartum hemorrhage

  • Dental procedures in hemophiliacs

  • Bleeding disorders including nosebleeds and trauma


 When Not to Use

Avoid if you have:

  • Active thromboembolic disease (DVT, PE)

  • Acquired color vision defects

  • Hypersensitivity to tranexamic acid

  • Subarachnoid hemorrhage

Precautions

  • Use with caution in patients with history of thrombosis or renal impairment

  • Not recommended in patients with irregular menstrual bleeding unless underlying cause is diagnosed

  • Ophthalmic exam may be required in long-term use

Warnings

  • Warning 1: May increase the risk of blood clots, especially in those with clotting disorders

  • Warning 2: Visual changes should be reported immediately

  • Warning 3: Dosage should be adjusted in renal impairment

Pregnancy Category

Category B – Safe when prescribed; use only under medical supervision, especially in the first trimester.

 Storage

  • Store below 25°C

  • Keep in original packaging

  • Protect from light and moisture

  • Keep out of reach of children