Yes
Tramadol Hydrochloride + Paracetamol
Moderate to severe pain relief
Tramadol: Opioid analgesic
Paracetamol: Analgesic and antipyretic
Tramal Plus combines two pain-relieving agents:
Tramadol: Alters how your body senses pain by acting on opioid receptors and inhibiting the reuptake of norepinephrine and serotonin.
Paracetamol (Acetaminophen): Reduces fever and pain by inhibiting prostaglandin synthesis in the brain.
Usually 1–2 tablets every 4–6 hours as needed
Do not exceed 8 tablets in 24 hours
Always follow your doctor’s instructions strictly
Nausea, dizziness, drowsiness, dry mouth, constipation
Respiratory depression, dependence/addiction, liver damage (with overdose), seizures, serotonin syndrome (especially with other serotonergic drugs)
CNS depressants (e.g., benzodiazepines, alcohol): Increased sedation and risk of respiratory depression
MAO inhibitors, SSRIs, and SNRIs: Risk of serotonin syndrome
Other paracetamol-containing medications: Risk of liver toxicity
Anticonvulsants and antidepressants: May increase seizure risk
Used for the relief of:
Post-operative pain
Chronic pain conditions
Back pain
Musculoskeletal pain
Pain from injury or trauma
Hypersensitivity to tramadol or paracetamol
Acute alcohol intoxication
Severe respiratory depression
Uncontrolled epilepsy
Patients taking MAO inhibitors
Not suitable for patients with a history of drug abuse or addiction
Use with caution in elderly patients, those with hepatic/renal dysfunction, and patients prone to seizures
Monitor closely for signs of overdose or abuse
Can cause addiction, especially with prolonged use.
Not suitable during pregnancy or breastfeeding unless prescribed under medical supervision.
Combining with alcohol, sedatives, or sleep aids increases risk of drowsiness and breathing problems.
C – Risk cannot be ruled out. Should only be used if absolutely necessary and prescribed.
Yes – Store at room temperature away from moisture and heat. Keep out of reach of children.
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