Requires Prescription (YES/NO): Yes
Generics: Naproxen Sodium
Used For: Pain relief, inflammation, arthritis, menstrual cramps
Class: Non-Steroidal Anti-Inflammatory Drug (NSAID)
How It Works
Synflex contains naproxen sodium, an NSAID that works by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes. This reduces the production of prostaglandins—chemicals responsible for pain, swelling, fever, and inflammation—providing long-lasting pain relief.
Usage and Safety
Dosage:
Adults: 250–500mg twice daily with food. Maximum 1000mg/day.
Children: Dose based on weight, only if prescribed by a doctor.
(Always follow doctor’s or label instructions. Do not exceed recommended dose.)
Side Effects:
Common: Heartburn, nausea, stomach pain, dizziness, headache.
Serious: Stomach/intestinal bleeding, ulcers, kidney problems, fluid retention, severe allergic reactions.
Drug Interactions:
Anticoagulants (e.g. warfarin) – increased bleeding risk
Other NSAIDs or corticosteroids – higher risk of stomach ulcers
ACE inhibitors/diuretics – reduced kidney function
Lithium or methotrexate – may increase toxicity
Alcohol – worsens stomach irritation & liver risk
🩺 Indication
Synflex is used for the treatment of:
Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis
Back pain, muscle pain, sprains
Headache, migraine
Menstrual cramps (dysmenorrhea)
Post-operative or dental pain
Fever and inflammatory conditions
🚫 When Not to Use
Avoid Synflex if you have:
Allergy to naproxen or other NSAIDs
Active stomach ulcer or gastrointestinal bleeding
Severe liver or kidney disease
Heart failure or history of stroke/heart attack
Asthma triggered by NSAIDs
Pregnancy (especially third trimester)
Precautions
Take with meals to reduce stomach irritation
Avoid combining with other NSAIDs unless prescribed
Monitor liver, kidney, and blood pressure in long-term use
Use with caution in elderly patients
Consult doctor if pregnant or breastfeeding
⚠️ Warnings
Warning 1: May increase risk of serious cardiovascular events (heart attack, stroke).
Warning 2: Prolonged use can cause stomach bleeding, ulceration, or perforation.
Warning 3: Use only under medical supervision in patients with heart, liver, or kidney disease.
Pregnancy Category
Not recommended during pregnancy (especially in the last trimester). Consult a doctor if pregnant or breastfeeding.
Storage
Store below 25°C, away from heat and moisture.
Keep in original packaging.
Keep out of reach of children.