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Generic Name: Betahistine Dihydrochloride
Drug Class: Histamine Analog (Anti-vertigo Agent)
Prescription Required: Yes
Meniere’s disease
Vertigo (dizziness)
Tinnitus (ringing in the ears)
Hearing loss associated with inner ear disorders
Serc (Betahistine) improves blood flow in the inner ear, which helps reduce the pressure buildup responsible for causing vertigo, tinnitus, and hearing loss. It acts as a histamine analog that balances fluid pressure in the inner ear (labyrinth), offering relief from symptoms of Meniere’s disease and similar conditions.
Typical adult dose:
16 mg tablet, taken two to three times daily with meals.
Always follow your doctor’s instructions regarding dosage and duration.
Common side effects may include:
Headache
Nausea
Indigestion (dyspepsia)
Abdominal bloating
Rare but serious side effects:
Allergic skin reactions (rash, itching)
Difficulty breathing (very rare)
Antihistamines (may reduce effectiveness of Serc)
Monoamine oxidase inhibitors (MAOIs) – can increase betahistine levels
Use caution with asthma medications
Allergy to betahistine
Patients with pheochromocytoma (a rare adrenal gland tumor)
Use with caution in asthma or gastric ulcer patients
Dosage:
Typically, one 16mg tablet is taken 2 to 3 times daily, preferably with meals to minimize stomach discomfort.
Administration:
Swallow the tablet whole with a full glass of water. Do not crush or chew the tablet.
Treatment Duration:
Improvement in symptoms may take a few weeks, and continued use as prescribed by your physician is necessary for optimal results.
Missed Dose:
Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed one. Do not double the dose.
Overdose:
Symptoms of overdose may include nausea, vomiting, seizures, and drowsiness. Seek immediate medical attention in such cases.
Not for pediatric use unless advised by a healthcare provider.
Avoid alcohol while taking this medicine as it can worsen dizziness.
Use with caution in individuals with:
Peptic ulcers (may increase gastric acid)
Bronchial asthma
Liver or kidney impairment
Driving/Operating Machinery:
Betahistine can cause drowsiness or dizziness in some individuals. Avoid such activities if affected.
Elderly Use:
Generally considered safe when used as prescribed, but dose adjustments may be needed depending on tolerance and comorbid conditions.
Use with caution in patients with a history of peptic ulcers
Monitor asthmatic patients closely
Safe use during pregnancy and lactation should be confirmed with a doctor
Do not take with antihistamines, as they may reduce the effectiveness of betahistine.
Monitor for stomach upset; take with food to minimize gastric side effects.
Not recommended for children under 18 unless prescribed.
Category C – Use only if benefits justify potential risks. Consult a doctor before use in pregnancy or breastfeeding.
Store below 25°C. Keep in a cool, dry place away from direct sunlight. Keep out of reach of children.
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