Panadol Tablets Specification

Requires Prescription (YES/NO)

Generics

Paracetamol

Used For

Pain & Fever

How It Works

Paracetamol exerts its analgesic (pain-relieving) and antipyretic (fever-reducing) effects by acting centrally in the brain. It is believed to work by inhibiting prostaglandin synthesis or influencing cannabinoid receptors through its active metabolites, although its exact mechanism remains debated.

Panadol Tablets Usage and Safety

Dosage

Adults & children above 12 years: 500mg to 1g (1 to 2 tablets) every 4 to 6 hours as needed.
Maximum daily dose: 4 grams (8 tablets).
Children below 12 years: Dosage should be determined by a healthcare professional.

Side Effects

Thrombocytopenia (low platelet count)
Anaphylaxis (severe allergic reaction)
Cutaneous hypersensitivity reactions, including:
- Skin rashes
- Angioedema (swelling)
- Stevens-Johnson Syndrome (SJS)
- Toxic Epidermal Necrolysis (TEN)
Bronchospasm in individuals sensitive to aspirin or NSAIDs
Hepatic dysfunction (liver damage)

Drug Interactions

Warfarin & other anticoagulants: Prolonged daily use of paracetamol may increase the risk of bleeding. Occasional use has no significant effect.

Indications

Panadol provides fast and effective relief from:

Headache
Migraine pain
Joint pain (Osteoarthritis)
Muscle ache
Toothache
Menstrual cramps
Fever

When Not to Use

Allergy to Paracetamol: Avoid use in individuals with known hypersensitivity to paracetamol or its excipients.

Panadol Tablets Precautions

Precaution

Do not take Panadol with other paracetamol-containing medications to prevent accidental overdose.

Panadol Tablets Warnings

Warning 1

Liver disease increases the risk of paracetamol-induced liver damage. Patients with liver or kidney impairment should consult a doctor before use.

Warning 2

Patients with low glutathione levels (such as those with malnutrition, low body mass index, anorexia, or chronic alcohol use) have a higher risk of liver damage when using Panadol.

Warning 3

Patients with sepsis and glutathione depletion may be at increased risk of metabolic acidosis when using paracetamol.

Panadol Tablets Additional Information

Pregnancy Category

Always consult a healthcare professional before using any medication during pregnancy.

Storage (YES/NO)

Yes – Store at room temperature, away from direct light and heat.

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