Panadol Extend Tablets

Panadol Extend Tablets Specification

Requires Prescription:

Generics:

Paracetamol

Used For:

Pain & Fever

How It Works

Paracetamol acts as a central analgesic, primarily by activating descending serotonergic pathways. While its exact mechanism remains debated, it is believed to either inhibit prostaglandin (PG) synthesis or exert its effects through an active metabolite that influences cannabinoid receptors.

Panadol Extend Tablets Usage & Safety

Dosage

Active Ingredient: Paracetamol

Side Effects

Thrombocytopenia (low platelet count)
Anaphylaxis and severe skin hypersensitivity reactions (e.g., rashes, angioedema, Stevens-Johnson Syndrome, toxic epidermal necrolysis)
Bronchospasm in individuals sensitive to aspirin or other NSAIDs
Hepatic dysfunction (liver issues)

Drug Interactions

Prolonged, regular use of paracetamol may enhance the anticoagulant effect of warfarin and other coumarins, increasing the risk of bleeding.
Occasional doses do not have a significant effect on anticoagulant activity.

Indications

Panadol Extend provides fast and effective relief from:

Headaches and migraines
Joint pain associated with osteoarthritis
Muscle aches
Toothaches
Period pain
Fever

When Not to Use

Do not take Panadol Extend if:

You have a history of hypersensitivity to paracetamol or any of its ingredients.

Panadol Extend Tablets Precautions

Important: Panadol Extend contains paracetamol. Avoid using other paracetamol-containing products simultaneously to prevent overdose.

Panadol Extend Tablet Warnings

Warning 1

Patients with underlying liver disease are at an increased risk of liver damage due to paracetamol. Those with liver or kidney impairment should seek medical advice before use.

Warning 2

Hepatic dysfunction or failure has been reported in individuals with depleted glutathione levels, including:

Those who are severely malnourished
Anorexic individuals
Those with a low body mass index (BMI)
Chronic heavy alcohol users

Warning 3

Patients with glutathione-depleted conditions, such as sepsis, may be at an increased risk of metabolic acidosis when using paracetamol.

Place Order